Mice Treated Subcutaneously with Mouse LPS-Converted PrP(res) or LPS Alone Showed Brain Gene Expression Profiles Characteristic of Prion Disease

Previously, we showed that bacterial lipopolysaccharide (LPS) converts mouse PrP(C) protein to a beta-rich isoform (moPrP(res)) resistant to proteinase K. In this study, we aimed to test if the LPS-converted PrP(res) is infectious and alters the expression of genes related to prion pathology in brai...

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Detalles Bibliográficos
Autores principales: Hailemariam, Dagnachew, Goldansaz, Seyed Ali, Daude, Nathalie, Wishart, David S., Ametaj, Burim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473295/
https://www.ncbi.nlm.nih.gov/pubmed/34564594
http://dx.doi.org/10.3390/vetsci8090200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473295/
https://www.ncbi.nlm.nih.gov/pubmed/34564594
http://dx.doi.org/10.3390/vetsci8090200

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