Predicting stable binding modes from simulated dimers of the D76N mutant of [Formula: see text] 2-microglobulin

The D76N mutant of the [Formula: see text] protein is a biologically motivated model system to study protein aggregation. There is strong experimental evidence, supported by molecular simulations, that D76N populates a highly dynamic conformation (which we originally named [Formula: see text]) that...

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Detalles Bibliográficos
Autores principales: Oliveira, Nuno F.B., Rodrigues, Filipe E.P., Vitorino, João N.M., Loureiro, Rui J.S., Faísca, Patrícia F.N., Machuqueiro, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473664/
https://www.ncbi.nlm.nih.gov/pubmed/34630936
http://dx.doi.org/10.1016/j.csbj.2021.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473664/
https://www.ncbi.nlm.nih.gov/pubmed/34630936
http://dx.doi.org/10.1016/j.csbj.2021.09.003

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