Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence

The main challenge in the treatment of acute myeloid leukemia (AML) is relapse, as it has no good treatment options and 90% of relapsed patients die as a result. It is now well accepted that relapse is due to a persisting subset of AML cells known as leukemia-initiating cells or leukemic stem cells...

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Detalles Bibliográficos
Autores principales: O’Reilly, Eimear, Zeinabad, Hojjat Alizadeh, Nolan, Caoimhe, Sefy, Jamileh, Williams, Thomas, Tarunina, Marina, Hernandez, Diana, Choo, Yen, Szegezdi, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473680/
https://www.ncbi.nlm.nih.gov/pubmed/34589478
http://dx.doi.org/10.3389/fcell.2021.662868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473680/
https://www.ncbi.nlm.nih.gov/pubmed/34589478
http://dx.doi.org/10.3389/fcell.2021.662868

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