Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia

The transcription factor Krueppel-like factor (KLF) 4 fosters the pro-inflammatory immune response in macrophages and polymorphonuclear neutrophils (PMNs) when stimulated with Streptococcus pneumoniae, the main causative pathogen of community-acquired pneumonia (CAP). Here, we investigated the impac...

Descripción completa

Detalles Bibliográficos
Autores principales: Herta, Toni, Bhattacharyya, Aritra, Rosolowski, Maciej, Conrad, Claudia, Gurtner, Corinne, Gruber, Achim D., Ahnert, Peter, Gutbier, Birgitt, Frey, Doris, Suttorp, Norbert, Hippenstiel, Stefan, Zahlten, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473698/
https://www.ncbi.nlm.nih.gov/pubmed/34589087
http://dx.doi.org/10.3389/fimmu.2021.726135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473698/
https://www.ncbi.nlm.nih.gov/pubmed/34589087
http://dx.doi.org/10.3389/fimmu.2021.726135

Ejemplares similares