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Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia

The transcription factor Krueppel-like factor (KLF) 4 fosters the pro-inflammatory immune response in macrophages and polymorphonuclear neutrophils (PMNs) when stimulated with Streptococcus pneumoniae, the main causative pathogen of community-acquired pneumonia (CAP). Here, we investigated the impac...

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Detalles Bibliográficos
Autores principales:	Herta, Toni, Bhattacharyya, Aritra, Rosolowski, Maciej, Conrad, Claudia, Gurtner, Corinne, Gruber, Achim D., Ahnert, Peter, Gutbier, Birgitt, Frey, Doris, Suttorp, Norbert, Hippenstiel, Stefan, Zahlten, Janine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473698/ https://www.ncbi.nlm.nih.gov/pubmed/34589087 http://dx.doi.org/10.3389/fimmu.2021.726135

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