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Elevated glycolysis imparts functional ability to CD8(+) T cells in HIV infection
The mechanisms inducing exhaustion of HIV-specific CD8(+) T cells are not fully understood. Metabolic programming directly influences T-cell differentiation, effector function, and memory. We evaluated metabolic profiles of ex vivo CD8(+) T cells in HIV-infected individuals. The baseline oxygen cons...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473722/ https://www.ncbi.nlm.nih.gov/pubmed/34548381 http://dx.doi.org/10.26508/lsa.202101081 |