Elevated glycolysis imparts functional ability to CD8(+) T cells in HIV infection

The mechanisms inducing exhaustion of HIV-specific CD8(+) T cells are not fully understood. Metabolic programming directly influences T-cell differentiation, effector function, and memory. We evaluated metabolic profiles of ex vivo CD8(+) T cells in HIV-infected individuals. The baseline oxygen cons...

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Detalles Bibliográficos
Autores principales: Rahman, AKM Nur-ur, Liu, Jun, Mujib, Shariq, Kidane, Segen, Ali, Arman, Szep, Steven, Han, Carrie, Bonner, Phil, Parsons, Michael, Benko, Erika, Kovacs, Colin, Yue, Feng Yun, Ostrowski, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473722/
https://www.ncbi.nlm.nih.gov/pubmed/34548381
http://dx.doi.org/10.26508/lsa.202101081

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