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Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling

B cell antigen receptor (BCR) signaling is initiated by protein kinases and limited by counteracting phosphatases that currently are less well studied in their regulation of BCR signaling. Here, we used the B cell line Ramos to identify and quantify human B cell signaling components. Specifically, a...

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Detalles Bibliográficos
Autores principales: Schwarz, Jennifer J, Grundmann, Lorenz, Kokot, Thomas, Kläsener, Kathrin, Fotteler, Sandra, Medgyesi, David, Köhn, Maja, Reth, Michael, Warscheid, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473724/
https://www.ncbi.nlm.nih.gov/pubmed/34526379
http://dx.doi.org/10.26508/lsa.202101084