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Transgenic overexpression of the miR-200b/200a/429 cluster inhibits mammary tumor initiation

The miR-200 family consists of five members expressed as two clusters: miR-200c/141 cluster and miR-200b/200a/429 cluster. In the mammary gland, miR-200s maintain epithelial identity by decreasing the expression of mesenchymal markers leading to high expression of epithelial markers. While the loss...

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Detalles Bibliográficos
Autores principales: Watson, Katrina L, Yi, Rui, Moorehead, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473771/
https://www.ncbi.nlm.nih.gov/pubmed/34562686
http://dx.doi.org/10.1016/j.tranon.2021.101228