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Transgenic overexpression of the miR-200b/200a/429 cluster inhibits mammary tumor initiation
The miR-200 family consists of five members expressed as two clusters: miR-200c/141 cluster and miR-200b/200a/429 cluster. In the mammary gland, miR-200s maintain epithelial identity by decreasing the expression of mesenchymal markers leading to high expression of epithelial markers. While the loss...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473771/ https://www.ncbi.nlm.nih.gov/pubmed/34562686 http://dx.doi.org/10.1016/j.tranon.2021.101228 |