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The Role of cAMP-PKA Pathway in Lactate-Induced Intramuscular Triglyceride Accumulation and Mitochondria Content Increase in Mice

The glycolytic product of exercise, lactate, has long been recognized to promote lipid accumulation by activation of G-protein-coupled receptor 81 (GPR81) and inhibition of the cyclic adenosine monophosphate-protein kinase A (cAMP –PKA) pathway in adipose tissue. Whether lactate causes a similar pro...

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Detalles Bibliográficos
Autores principales: Chen, Siyu, Zhou, Lei, Sun, Jingquan, Qu, Yaqian, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473783/
https://www.ncbi.nlm.nih.gov/pubmed/34588991
http://dx.doi.org/10.3389/fphys.2021.709135