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Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate

In the aorta-gonad-mesonephros (AGM) region of mouse embryos, pre-hematopoietic stem cells (pre-HSCs) are generated from rare and specialized hemogenic endothelial cells (HECs) via endothelial-to-hematopoietic transition, followed by maturation into bona fide hematopoietic stem cells (HSCs). As HECs...

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Detalles Bibliográficos
Autores principales: Tang, Wanbo, He, Jian, Huang, Tao, Bai, Zhijie, Wang, Chaojie, Wang, Haizhen, Yang, Ruichuang, Ni, Yanli, Hou, Jun, Wang, Junliang, Zhou, Jie, Yao, Yingpeng, Gong, Yandong, Hou, Siyuan, Liu, Bing, Lan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473784/
https://www.ncbi.nlm.nih.gov/pubmed/34589491
http://dx.doi.org/10.3389/fcell.2021.728057