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Targeting M2 Macrophages Alleviates Airway Inflammation and Remodeling in Asthmatic Mice via miR-378a-3p/GRB2 Pathway

Background: Asthma is a complex respiratory disease characterized by airway inflammation and remodeling. MicroRNAs (miRNAs) mediate various cellular processes including macrophage polarization and play an important role in the pathogenesis of asthma. In present study, we aimed to screen miRNA profil...

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Detalles Bibliográficos
Autores principales: Wang, Qiujie, Hong, Luna, Chen, Ming, Shi, Jiangting, Lin, Xiaoling, Huang, Linjie, Tang, Tiantian, Guo, Yimin, Yuan, Xiaoqing, Jiang, Shanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473897/
https://www.ncbi.nlm.nih.gov/pubmed/34589519
http://dx.doi.org/10.3389/fmolb.2021.717969