Loss of Growth Differentiation Factor 11 Shortens Telomere Length by Downregulating Telomerase Activity

Maintenance of telomere length is essential to delay replicative cellular senescence. It is controversial on whether growth differentiation factor 11 (GDF11) can reverse cellular senescence, and this work aims to establish the causality between GDF11 and the telomere maintenance unequivocally. Using...

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Detalles Bibliográficos
Autores principales: Wang, Di-Xian, Zhu, Xu-Dong, Ma, Xiao-Ru, Wang, Li-Bin, Dong, Zhao-Jun, Lin, Rong-Rong, Cao, Yi-Na, Zhao, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473905/
https://www.ncbi.nlm.nih.gov/pubmed/34588995
http://dx.doi.org/10.3389/fphys.2021.726345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473905/
https://www.ncbi.nlm.nih.gov/pubmed/34588995
http://dx.doi.org/10.3389/fphys.2021.726345

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