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The amino acid substitution affects cellular response to mistranslation

Mistranslation, the misincorporation of an amino acid not specified by the “standard” genetic code, occurs in all organisms. tRNA variants that increase mistranslation arise spontaneously and engineered tRNAs can achieve mistranslation frequencies approaching 10% in yeast and bacteria. Interestingly...

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Detalles Bibliográficos
Autores principales: Berg, Matthew D, Zhu, Yanrui, Ruiz, Bianca Y, Loll-Krippleber, Raphaël, Isaacson, Joshua, San Luis, Bryan-Joseph, Genereaux, Julie, Boone, Charles, Villén, Judit, Brown, Grant W, Brandl, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473984/
https://www.ncbi.nlm.nih.gov/pubmed/34568909
http://dx.doi.org/10.1093/g3journal/jkab218