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The amino acid substitution affects cellular response to mistranslation
Mistranslation, the misincorporation of an amino acid not specified by the “standard” genetic code, occurs in all organisms. tRNA variants that increase mistranslation arise spontaneously and engineered tRNAs can achieve mistranslation frequencies approaching 10% in yeast and bacteria. Interestingly...
Autores principales: | Berg, Matthew D, Zhu, Yanrui, Ruiz, Bianca Y, Loll-Krippleber, Raphaël, Isaacson, Joshua, San Luis, Bryan-Joseph, Genereaux, Julie, Boone, Charles, Villén, Judit, Brown, Grant W, Brandl, Christopher J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473984/ https://www.ncbi.nlm.nih.gov/pubmed/34568909 http://dx.doi.org/10.1093/g3journal/jkab218 |
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