Mechanisms of inhibition of viral RNA replication by nucleotide analogs

Nucleotide analogs are the cornerstone of direct acting antivirals used to control infection by RNA viruses. Here we review what is known about existing nucleotide/nucleoside analogs and the kinetics and mechanisms of RNA and DNA replication, with emphasis on the SARS-CoV-2 RNA dependent RNA polymer...

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Detalles Bibliográficos
Autores principales: Johnson, Kenneth A., Dangerfield, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474024/
https://www.ncbi.nlm.nih.gov/pubmed/34696838
http://dx.doi.org/10.1016/bs.enz.2021.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474024/
https://www.ncbi.nlm.nih.gov/pubmed/34696838
http://dx.doi.org/10.1016/bs.enz.2021.07.001

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