From Propargylic Alcohols to Substituted Thiochromenes: gem-Disubstituent Effect in Intramolecular Alkyne Iodo/hydroarylation

[Image: see text] This work describes the 6-endo-dig cyclization of S-aryl propargyl sulfides to afford 2H-thiochromenes. The substitution at the propargylic position plays a crucial role in allowing intramolecular silver-catalyzed alkyne hydroarylation and N-iodosuccinimide-promoted iodoarylation....

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Detalles Bibliográficos
Autores principales: Velasco, Noelia, Suárez, Anisley, Martínez-Lara, Fernando, Fernández-Rodríguez, Manuel Ángel, Sanz, Roberto, Suárez-Pantiga, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474117/
https://www.ncbi.nlm.nih.gov/pubmed/33928778
http://dx.doi.org/10.1021/acs.joc.1c00333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474117/
https://www.ncbi.nlm.nih.gov/pubmed/33928778
http://dx.doi.org/10.1021/acs.joc.1c00333

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