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Afatinib as a Potential Therapeutic Option for Patients With NSCLC With EGFR G724S

INTRODUCTION: EGFR G724S has been described to mediate resistance to first- and third-generation EGFR tyrosine kinase inhibitors (TKIs). In vitro experiments have provided compelling evidence that G724S retains sensitivity for afatinib. Nevertheless, limited data have reported the clinical efficacy...

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Detalles Bibliográficos
Autores principales: Wei, Yang, Jiang, Benyuan, Liu, Shulin, Zhang, Zhonghan, Fang, Wenfeng, Yang, Yunpeng, Li, Xin, Zhao, Jingyi, Zhao, Hongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474270/
https://www.ncbi.nlm.nih.gov/pubmed/34590038
http://dx.doi.org/10.1016/j.jtocrr.2021.100193