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Afatinib as a Potential Therapeutic Option for Patients With NSCLC With EGFR G724S
INTRODUCTION: EGFR G724S has been described to mediate resistance to first- and third-generation EGFR tyrosine kinase inhibitors (TKIs). In vitro experiments have provided compelling evidence that G724S retains sensitivity for afatinib. Nevertheless, limited data have reported the clinical efficacy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474270/ https://www.ncbi.nlm.nih.gov/pubmed/34590038 http://dx.doi.org/10.1016/j.jtocrr.2021.100193 |