JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes–Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies

INTRODUCTION: JNJ-64041757 (JNJ-757) is a live, attenuated, double-deleted Listeria monocytogenes–based immunotherapy expressing human mesothelin. JNJ-757 was evaluated in patients with advanced NSCLC as monotherapy (phase 1) and in combination with nivolumab (phase 1b/2). METHODS: Patients with sta...

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Detalles Bibliográficos
Autores principales: Brahmer, Julie R., Johnson, Melissa L., Cobo, Manuel, Viteri, Santiago, Sarto, Juan Coves, Sukari, Ammar, Awad, Mark M., Salgia, Ravi, Papadimitrakopoulou, Vali A., Rajan, Arun, Bandyopadhyay, Nibedita, Allred, Alicia J., Wade, Mark, Mason, Gary E., Zudaire, Enrique, Knoblauch, Roland E., Stone, Nicole, Lorenzi, Matthew V., Hassan, Raffit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474274/
https://www.ncbi.nlm.nih.gov/pubmed/34589981
http://dx.doi.org/10.1016/j.jtocrr.2020.100103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474274/
https://www.ncbi.nlm.nih.gov/pubmed/34589981
http://dx.doi.org/10.1016/j.jtocrr.2020.100103

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