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JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes–Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies
INTRODUCTION: JNJ-64041757 (JNJ-757) is a live, attenuated, double-deleted Listeria monocytogenes–based immunotherapy expressing human mesothelin. JNJ-757 was evaluated in patients with advanced NSCLC as monotherapy (phase 1) and in combination with nivolumab (phase 1b/2). METHODS: Patients with sta...
Autores principales: | Brahmer, Julie R., Johnson, Melissa L., Cobo, Manuel, Viteri, Santiago, Sarto, Juan Coves, Sukari, Ammar, Awad, Mark M., Salgia, Ravi, Papadimitrakopoulou, Vali A., Rajan, Arun, Bandyopadhyay, Nibedita, Allred, Alicia J., Wade, Mark, Mason, Gary E., Zudaire, Enrique, Knoblauch, Roland E., Stone, Nicole, Lorenzi, Matthew V., Hassan, Raffit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474274/ https://www.ncbi.nlm.nih.gov/pubmed/34589981 http://dx.doi.org/10.1016/j.jtocrr.2020.100103 |
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