Brief Report: Heterogeneity of Acquired Resistance Mechanisms to Osimertinib and Savolitinib

INTRODUCTION: MET amplification is a frequently observed mechanism of resistance to osimertinib, and coinhibition strategy of MET and EGFR revealed promising results in recent clinical trials. Nevertheless, acquired resistance mechanisms to combined EGFR and MET inhibition are poorly understood. In...

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Detalles Bibliográficos
Autores principales: Lim, Sun Min, Yang, San-Duk, Lim, Sangbin, Shim, Hyo Sup, Cho, Byoung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474358/
https://www.ncbi.nlm.nih.gov/pubmed/34590028
http://dx.doi.org/10.1016/j.jtocrr.2021.100180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474358/
https://www.ncbi.nlm.nih.gov/pubmed/34590028
http://dx.doi.org/10.1016/j.jtocrr.2021.100180

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