Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation

INTRODUCTION: A subset of lung adenocarcinomas (ADs) has been found to have somatic activating mutations in the tyrosine kinase domain of the EGFR gene, associated with response to EGFR tyrosine kinase inhibitor therapy. Rare germline mutations within this domain, including EGFR T790M, have been ass...

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Detalles Bibliográficos
Autores principales: Mäkinen, Netta, Zhou, Meng, Bemus, Meredith, Nevin, Julius, Nag, Anwesha, Chen, Ruthia, Colson, Yolonda L., Thorner, Aaron R., Oxnard, Geoffrey R., Meyerson, Matthew, Sholl, Lynette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474413/
https://www.ncbi.nlm.nih.gov/pubmed/34590005
http://dx.doi.org/10.1016/j.jtocrr.2021.100146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474413/
https://www.ncbi.nlm.nih.gov/pubmed/34590005
http://dx.doi.org/10.1016/j.jtocrr.2021.100146

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