Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation
INTRODUCTION: A subset of lung adenocarcinomas (ADs) has been found to have somatic activating mutations in the tyrosine kinase domain of the EGFR gene, associated with response to EGFR tyrosine kinase inhibitor therapy. Rare germline mutations within this domain, including EGFR T790M, have been ass...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474413/ https://www.ncbi.nlm.nih.gov/pubmed/34590005 http://dx.doi.org/10.1016/j.jtocrr.2021.100146 |