Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC

INTRODUCTION: Estrogen receptors (ER) (ERα, ERβ) and aromatase (key enzyme for estrogen synthesis) are expressed in most human NSCLCs. High intratumoral estrogen levels and elevated aromatase expression in NSCLC predict poor outcome. This open-label, phase 1b, single-center study evaluated the safet...

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Detalles Bibliográficos
Autores principales: Young, Patricia A., Márquez-Garbán, Diana C., Noor, Zorawar Singh, Moatamed, Neda, Elashoff, David, Grogan, Tristan, Romero, Tahmineh, Sasano, Hironobu, Saito, Ryoko, Rausch, Rebecca, Hamilton, Nalo, Dubinett, Steven M., Garon, Edward B., Pietras, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474426/
https://www.ncbi.nlm.nih.gov/pubmed/34590007
http://dx.doi.org/10.1016/j.jtocrr.2021.100150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474426/
https://www.ncbi.nlm.nih.gov/pubmed/34590007
http://dx.doi.org/10.1016/j.jtocrr.2021.100150

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