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Differentially expressed genes in Alzheimer’s disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1

BACKGROUND: Alzheimer’s disease (AD) is associated with abnormal tau and amyloid-β accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and extracellular amyloid-β plaques. Treatment is limited to symptom management, a disease-modifying therapy is not available. To advance...

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Detalles Bibliográficos
Autores principales: Li, Qingqin S., De Muynck, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474442/
https://www.ncbi.nlm.nih.gov/pubmed/34589742
http://dx.doi.org/10.1016/j.bbih.2021.100227