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Differentially expressed genes in Alzheimer’s disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1
BACKGROUND: Alzheimer’s disease (AD) is associated with abnormal tau and amyloid-β accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and extracellular amyloid-β plaques. Treatment is limited to symptom management, a disease-modifying therapy is not available. To advance...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474442/ https://www.ncbi.nlm.nih.gov/pubmed/34589742 http://dx.doi.org/10.1016/j.bbih.2021.100227 |