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ASD-like behaviors, a dysregulated inflammatory response and decreased expression of PLP1 characterize mice deficient for sialyltransferase ST3GAL5

Gangliosides are glycosphingolipids, which are abundant in brain, are known to modulate ion channels and cell-to-cell communication. Deficiencies can result in aberrant myelination and altered immune responses, which can give rise to neurodevelopmental psychiatric disorders. However, to date, little...

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Detalles Bibliográficos
Autores principales: Strekalova, Tatyana, Svirin, Evgeniy, Veniaminova, Ekaterina, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W.Y., Proshin, Andrey, Walitza, Susanne, Anthony, Daniel C., Lim, Lee Wei, Lesch, Klaus-Peter, Ponomarev, Eugene D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474501/
https://www.ncbi.nlm.nih.gov/pubmed/34589798
http://dx.doi.org/10.1016/j.bbih.2021.100306