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Exploring the roles of tryptophan metabolism in MS beyond neuroinflammation and neurodegeneration: A paradigm shift to neuropsychiatric symptoms

The metabolism of tryptophan through the kynurenine pathway (KP) has been increasingly recognised in contributing to disease progression in the autoimmune and inflammatory disease multiple sclerosis (MS). In this review, the roles of inflammation and the KP are recontextualised to better understand...

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Detalles Bibliográficos
Autores principales: Tan, Lorraine S.Y., Francis, Heather M., Lim, Chai K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474511/
https://www.ncbi.nlm.nih.gov/pubmed/34589733
http://dx.doi.org/10.1016/j.bbih.2021.100201