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Intranasal HSP70 administration protects against dopaminergic denervation and modulates neuroinflammatory response in the 6-OHDA rat model

HSP70 is one of the main molecular chaperones involved in the cellular stress response. Besides its chaperone action, HSP70 also modulates the immune response. Increased susceptibility to toxic insults in intra- and extracellular environments has been associated with insufficient amounts of inducibl...

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Detalles Bibliográficos
Autores principales: Tiefensee Ribeiro, Camila, Peixoto, Daniel Oppermann, Santos, Lucas, Saibro-Girardi, Carolina, Brum, Pedro Ozorio, Carazza-Kessler, Flávio Gabriel, Somensi, Nauana, Behrens, Luiza Marques Prates, Bittencourt, Reykla Ramon, Soares, Laíssa Santos, Silveira, Alexandre Kleber, de Oliveira, Jade, Moreira, José Cláudio Fonseca, Gasparotto, Juciano, Gelain, Daniel Pens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474599/
https://www.ncbi.nlm.nih.gov/pubmed/34589762
http://dx.doi.org/10.1016/j.bbih.2021.100253