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Sleep restriction prior to antigen exposure does not alter the T cell receptor repertoire but impairs germinal center formation during a T cell-dependent B cell response in murine spleen

It is well known that sleep promotes immune functions. In line with this, a variety of studies in animal models and humans have shown that sleep restriction following an antigen challenge dampens the immune response on several levels which leads to e.g. worsening of disease outcome and reduction of...

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Detalles Bibliográficos
Autores principales: Tune, Cornelia, Hahn, Julia, Autenrieth, Stella E., Meinhardt, Martin, Pagel, Rene, Schampel, Andrea, Schierloh, Lisa-Kristin, Kalies, Kathrin, Westermann, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474616/
https://www.ncbi.nlm.nih.gov/pubmed/34589803
http://dx.doi.org/10.1016/j.bbih.2021.100312