Kynurenine pathway metabolites selectively associate with impaired associative memory function in depression

Activation of the kynurenine pathway (KP), an important downstream effect of inflammation, is a driver of depression and neurodegeneration. Damage from the end product of KP activation, quinolinic acid, may be responsible specifically for impairment in hippocampally mediated memory function, among i...

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Detalles Bibliográficos
Autores principales: Chirico, Margherita, Custer, James, Shoyombo, Ifeoluwa, Cooper, Crystal, Meldrum, Sheila, Dantzer, Robert, Trivedi, Madhukar H., Rathouz, Paul, Toups, Marisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474644/
https://www.ncbi.nlm.nih.gov/pubmed/34589879
http://dx.doi.org/10.1016/j.bbih.2020.100126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474644/
https://www.ncbi.nlm.nih.gov/pubmed/34589879
http://dx.doi.org/10.1016/j.bbih.2020.100126

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