Endogenous microRNA triggered enzyme-free DNA logic self-assembly for amplified bioimaging and enhanced gene therapy via in situ generation of siRNAs

BACKGROUND: Small interfering RNA (siRNA) has emerged as a kind of promising therapeutic agents for cancer therapy. However, the off-target effect and degradation are the main challenges for siRNAs delivery. Herein, an enzyme-free DNA amplification strategy initiated by a specific endogenous microRN...

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Detalles Bibliográficos
Autores principales: Jiang, Qinghua, Yue, Shuzhen, Yu, Kaixin, Tian, Tian, Zhang, Jian, Chu, Huijun, Cui, Zhumei, Bi, Sai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474761/
https://www.ncbi.nlm.nih.gov/pubmed/34565382
http://dx.doi.org/10.1186/s12951-021-01040-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474761/
https://www.ncbi.nlm.nih.gov/pubmed/34565382
http://dx.doi.org/10.1186/s12951-021-01040-x

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