A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans

BACKGROUND: During pregnancy, the mouse mammary ductal epithelium branches and grows into the surrounding stroma, requiring extensive extracellular matrix (ECM) and tissue remodelling. It therefore shows parallels to cancer invasion. We hypothesised that similar molecular mechanisms may be utilised...

Descripción completa

Detalles Bibliográficos
Autores principales: Ibrahim, Ayman M., Bilsland, Alan, Rickelt, Steffen, Morris, Joanna S., Stein, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474794/
https://www.ncbi.nlm.nih.gov/pubmed/34565423
http://dx.doi.org/10.1186/s13058-021-01470-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474794/
https://www.ncbi.nlm.nih.gov/pubmed/34565423
http://dx.doi.org/10.1186/s13058-021-01470-3

Ejemplares similares