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Study protocol: DexaDays-2, hydrocortisone for treatment of dexamethasone-induced neurobehavioral side effects in pediatric leukemia patients: a double-blind placebo controlled randomized intervention study with cross-over design

BACKGROUND: Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as detrimental with respect to health related quality of life (HRQoL). Based on pre...

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Detalles Bibliográficos
Autores principales: van Hulst, A. M., Verwaaijen, E. J., Fiocco, M. F., Pluijm, S. M. F., Grootenhuis, M. A., Pieters, R., van den Akker, E. L. T., van den Heuvel-Eibrink, M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474814/
https://www.ncbi.nlm.nih.gov/pubmed/34579671
http://dx.doi.org/10.1186/s12887-021-02896-6