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Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition

BACKGROUND: DNA methylation plays a crucial role in multiple cellular processes such as gene regulation, chromatin stability, and genetic imprinting. In mammals, DNA methylation is achieved by DNA methyltransferases (DNMTs). A number of studies have associated alterations in DNMT activity to tumorig...

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Detalles Bibliográficos
Autores principales: Elango, Ramesh, Vishnubalaji, Radhakrishnan, Shaath, Hibah, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474815/
https://www.ncbi.nlm.nih.gov/pubmed/34565361
http://dx.doi.org/10.1186/s12935-021-02213-2