Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice

BACKGROUND: Destruction of blood–brain barrier (BBB) ​​is one of the main mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Frizzled-7 is a key protein expressed on the surface of endothelial cells that controls vascular permeability through the Wnt-canonical pathway inv...

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Detalles Bibliográficos
Autores principales: He, Wei, Lu, Qin, Sherchan, Prativa, Huang, Lei, Hu, Xin, Zhang, John H., Dai, Haibin, Tang, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474841/
https://www.ncbi.nlm.nih.gov/pubmed/34565396
http://dx.doi.org/10.1186/s12987-021-00278-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474841/
https://www.ncbi.nlm.nih.gov/pubmed/34565396
http://dx.doi.org/10.1186/s12987-021-00278-9

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