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Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice
BACKGROUND: Destruction of blood–brain barrier (BBB) is one of the main mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Frizzled-7 is a key protein expressed on the surface of endothelial cells that controls vascular permeability through the Wnt-canonical pathway inv...
Autores principales: | He, Wei, Lu, Qin, Sherchan, Prativa, Huang, Lei, Hu, Xin, Zhang, John H., Dai, Haibin, Tang, Jiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474841/ https://www.ncbi.nlm.nih.gov/pubmed/34565396 http://dx.doi.org/10.1186/s12987-021-00278-9 |
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