A targeted solution for estimating the cell-type composition of bulk samples

BACKGROUND: To avoid false-positive findings and detect cell-type specific associations in methylation and transcription investigations with bulk samples, it is critical to know the proportions of the major cell-types. RESULTS: We present a novel approach that allows for precise estimation of cell-t...

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Detalles Bibliográficos
Autores principales: van den Oord, Edwin J. C. G., Xie, Lin Y., Tran, Charles J., Zhao, Min, Aberg, Karolina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474864/
https://www.ncbi.nlm.nih.gov/pubmed/34565346
http://dx.doi.org/10.1186/s12859-021-04385-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474864/
https://www.ncbi.nlm.nih.gov/pubmed/34565346
http://dx.doi.org/10.1186/s12859-021-04385-0

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