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A targeted solution for estimating the cell-type composition of bulk samples

BACKGROUND: To avoid false-positive findings and detect cell-type specific associations in methylation and transcription investigations with bulk samples, it is critical to know the proportions of the major cell-types. RESULTS: We present a novel approach that allows for precise estimation of cell-t...

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Detalles Bibliográficos
Autores principales:	van den Oord, Edwin J. C. G., Xie, Lin Y., Tran, Charles J., Zhao, Min, Aberg, Karolina A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474864/ https://www.ncbi.nlm.nih.gov/pubmed/34565346 http://dx.doi.org/10.1186/s12859-021-04385-0

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