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p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

BACKGROUND: Metabolic reprogramming sustains tumorigenesis and aggressiveness of neuroblastoma (NB), the most common extracranial malignancy in childhood, while underlying mechanisms and therapeutic approaches still remain elusive. METHODS: Circular RNAs (circRNAs) were validated by Sanger sequencin...

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Detalles Bibliográficos
Autores principales: Yang, Feng, Hu, Anpei, Guo, Yanhua, Wang, Jianqun, Li, Dan, Wang, Xiaojing, Jin, Shikai, Yuan, Boling, Cai, Shuang, Zhou, Yi, Li, Qilan, Chen, Guo, Gao, Haiyang, Zheng, Liduan, Tong, Qiangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474885/
https://www.ncbi.nlm.nih.gov/pubmed/34579723
http://dx.doi.org/10.1186/s12943-021-01421-8