Cargando…

p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

BACKGROUND: Metabolic reprogramming sustains tumorigenesis and aggressiveness of neuroblastoma (NB), the most common extracranial malignancy in childhood, while underlying mechanisms and therapeutic approaches still remain elusive. METHODS: Circular RNAs (circRNAs) were validated by Sanger sequencin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Feng, Hu, Anpei, Guo, Yanhua, Wang, Jianqun, Li, Dan, Wang, Xiaojing, Jin, Shikai, Yuan, Boling, Cai, Shuang, Zhou, Yi, Li, Qilan, Chen, Guo, Gao, Haiyang, Zheng, Liduan, Tong, Qiangsong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474885/ https://www.ncbi.nlm.nih.gov/pubmed/34579723 http://dx.doi.org/10.1186/s12943-021-01421-8

Ejemplares similares

Therapeutic targeting of SPIB/SPI1‐facilitated interplay of cancer cells and neutrophils inhibits aerobic glycolysis and cancer progression
por: Wang, Jianqun, et al.
Publicado: (2021)

Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression
por: Li, Huanhuan, et al.
Publicado: (2019)

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2019)

Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2023)

Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity
por: Hu, Anpei, et al.
Publicado: (2023)

Long-Term Survival of Neuroblastoma Patients Receiving Surgery, Chemotherapy, and Radiotherapy: A Propensity Score Matching Study
por: Li, Qilan, et al.
Publicado: (2023)

Therapeutic Targeting of MZF1‐AS1/PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression
por: Fang, Erhu, et al.
Publicado: (2019)

Robot-Assisted versus Trans-Umbilical Multiport Laparoscopic Ureteral Reimplantation for Pediatric Benign Distal Ureteral Stricture: Mid-Term Results at a Single Center
por: Guo, Yanhua, et al.
Publicado: (2022)

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression
por: Fang, Erhu, et al.
Publicado: (2020)

RETRACTED ARTICLE: HNF4A-AS1/hnRNPU/CTCF axis as a therapeutic target for aerobic glycolysis and neuroblastoma progression
por: Song, Huajie, et al.
Publicado: (2020)

Retraction Note: HNF4A-AS1/hnRNPU/CTCF axis as a therapeutic target for aerobic glycolysis and neuroblastoma progression
por: Song, Huajie, et al.
Publicado: (2023)

circ-hnRNPU inhibits NONO-mediated c-Myc transactivation and mRNA stabilization essential for glycosylation and cancer progression
por: Li, Hongjun, et al.
Publicado: (2023)

Genomic studies controvert the existence of the CUX1 p75 isoform
por: Krishnan, Manisha, et al.
Publicado: (2022)

Zrf1 is required to establish and maintain neural progenitor identity
por: Aloia, Luigi, et al.
Publicado: (2014)

Data on CUX1 isoforms in idiopathic pulmonary fibrosis lung and systemic sclerosis skin tissue sections
por: Ikeda, Tetsurou, et al.
Publicado: (2016)

Inactivating CUX1 mutations promote tumorigenesis
por: Wong, Chi C., et al.
Publicado: (2013)

Transforming growth factor-β-induced CUX1 isoforms are associated with fibrosis in systemic sclerosis lung fibroblasts
por: Ikeda, Tetsurou, et al.
Publicado: (2016)

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
por: Li, Zichong, et al.
Publicado: (2013)

The DNA repair function of CUX1 contributes to radioresistance
por: Ramdzan, Zubaidah M., et al.
Publicado: (2017)

CUX1, A Controversial Player in Tumor Development
por: Liu, Ning, et al.
Publicado: (2020)

ZRF1 is a novel S6 kinase substrate that drives the senescence programme
por: Barilari, Manuela, et al.
Publicado: (2017)

DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair
por: Chitale, Shalaka, et al.
Publicado: (2017)

A Novel Epigenetic Regulator ZRF1: Insight into Its Functions in Plants
por: Feng, Jing, et al.
Publicado: (2021)

The role of CUX1 in antagonizing NF-κB signaling in TAMs
por: Kühnemuth, Benjamin, et al.
Publicado: (2014)

Phosphofructokinase 1 Platelet Isoform Promotes β-Catenin Transactivation for Tumor Development
por: Lee, Jong-Ho, et al.
Publicado: (2020)

Role for the transcriptional activator ZRF1 in early metastatic events in breast cancer progression and endocrine resistance
por: Kaymak, Aysegül, et al.
Publicado: (2018)

The Transcription Factor Cux1 Regulates Dendritic Morphology of Cortical Pyramidal Neurons
por: Li, Ning, et al.
Publicado: (2010)

RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage
por: Ramdzan, Zubaidah M., et al.
Publicado: (2014)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
por: Krug, Sebastian, et al.
Publicado: (2020)

1,1,3-Trimethyl-3-phenylindane
por: Men, Jian, et al.
Publicado: (2008)

Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades
por: Dyachenko, Lada, et al.
Publicado: (2016)

Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation
por: Khan, Nabab, et al.
Publicado: (2018)

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice
por: Siam, Rania, et al.
Publicado: (2009)

Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers
por: Vadnais, Charles, et al.
Publicado: (2014)

ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair
por: Gracheva, Ekaterina, et al.
Publicado: (2016)

UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence
por: De Magis, Alessio, et al.
Publicado: (2023)

Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation
por: Wang, Pengxia, et al.
Publicado: (2018)

CUX2 functions as an oncogene in papillary thyroid cancer
por: Sun, Yihan, et al.
Publicado: (2018)

Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification
por: Fernandez‐Alonso, Rosalia, et al.
Publicado: (2017)

Cloning BRD4 long isoform into overexpression vectors for stable overexpression of BRD4-L in mammalian cells
por: Drumond-Bock, Ana Luiza, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ru2bs5247b6nbto6c2it1vnqe5