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Krüppel‐Like Factor 15/Interleukin 11 Axis‐Mediated Adventitial Remodeling Depends on Extracellular Signal‐Regulated Kinases 1 and 2 Activation in Angiotensin II–Induced Hypertension

BACKGROUND: Adventitial remodeling is a pathological hallmark of hypertension that results in target organ damage. Activated adventitial fibroblasts have emerged as critical regulators in this process, but the precise mechanism remains unclear. METHODS AND RESULTS: Interleukin 11 (IL‐11) knockout an...

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Detalles Bibliográficos
Autores principales: Guo, Yue‐Tong, Lu, Yuan‐Yuan, Lu, Xiao, He, Shun, Li, Shi‐Jin, Shao, Shuai, Zhou, Han‐Dan, Wang, Rui‐Qi, Li, Xiao‐Dong, Gao, Ping‐Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475029/
https://www.ncbi.nlm.nih.gov/pubmed/34350769
http://dx.doi.org/10.1161/JAHA.120.020554