Improved anticancer activity of betulinic acid on breast cancer through a grafted copolymer-based micelles system

Betulinic acid (3β-Hydroxy-20(29)-lupaene-28-oic acid, BA) has excellent anti-cancer activity but poor solubility and low bioavailability. To improve the antitumor activity of BA, a polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol (PVCL–PVA–PEG) graft copolymer (Soluplus) encapsulated BA...

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Detalles Bibliográficos
Autores principales: Qi, Xueju, Gao, Cong, Yin, Chuanjin, Fan, Junting, Wu, Xiaochen, Guo, Chuanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475105/
https://www.ncbi.nlm.nih.gov/pubmed/34565273
http://dx.doi.org/10.1080/10717544.2021.1979125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475105/
https://www.ncbi.nlm.nih.gov/pubmed/34565273
http://dx.doi.org/10.1080/10717544.2021.1979125

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