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Improved anticancer activity of betulinic acid on breast cancer through a grafted copolymer-based micelles system
Betulinic acid (3β-Hydroxy-20(29)-lupaene-28-oic acid, BA) has excellent anti-cancer activity but poor solubility and low bioavailability. To improve the antitumor activity of BA, a polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol (PVCL–PVA–PEG) graft copolymer (Soluplus) encapsulated BA...
Autores principales: | Qi, Xueju, Gao, Cong, Yin, Chuanjin, Fan, Junting, Wu, Xiaochen, Guo, Chuanlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475105/ https://www.ncbi.nlm.nih.gov/pubmed/34565273 http://dx.doi.org/10.1080/10717544.2021.1979125 |
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