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BESPOKE study protocol: a multicentre, prospective observational study to evaluate the impact of circulating tumour DNA guided therapy on patients with colorectal cancer

INTRODUCTION: Colorectal cancer (CRC) is a highly prevalent disease, wherein, ~30%–40% of patients with CRC relapse postresection. In some patients with CRC, adjuvant chemotherapy can help delay recurrence or be curative. However, current biomarkers show limited clinical utility in determining if/wh...

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Detalles Bibliográficos
Autores principales: Kasi, Pashtoon Murtaza, Sawyer, Sarah, Guilford, Jessica, Munro, Michelle, Ellers, Sascha, Wulff, Jacob, Hook, Nicole, Krinshpun, Shifra, Koyen Malashevich, Allyson, Malhotra, Meenakshi, Rodriguez, Angel, Moshkevich, Solomon, Grothey, Axel, Kopetz, Scott, Billings, Paul, Aleshin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475162/
https://www.ncbi.nlm.nih.gov/pubmed/34561256
http://dx.doi.org/10.1136/bmjopen-2020-047831