Development of CMV-CD19 bi-specific CAR T cells with post-infusion in vivo boost using an anti-CMV vaccine

Adoptive transfer of in vitro expanded, chimeric antigen receptor (CAR)-redirected CD19-specific T cells can induce dramatic disease regression in patients with leukemia and lymphomas. However, the full potential of this emerging modality is hampered in some cancer settings by a significant rate of...

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Detalles Bibliográficos
Autores principales: Wang, Xiuli, Diamond, Don J., Forman, Stephen J., Nakamura, Ryotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Progress in Hematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475363/
https://www.ncbi.nlm.nih.gov/pubmed/34561840
http://dx.doi.org/10.1007/s12185-021-03215-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475363/
https://www.ncbi.nlm.nih.gov/pubmed/34561840
http://dx.doi.org/10.1007/s12185-021-03215-6

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