Mechanism of Cross-Resistance to Fusion Inhibitors Conferred by the K394R Mutation in Respiratory Syncytial Virus Fusion Protein

The fusion glycoprotein (F) is essential for respiratory syncytial virus (RSV) entry and has become an attractive target for anti-RSV drug development. Despite the promising prospect of RSV F inhibitors, issues of drug resistance remain challenging. In this study, we established a dual-luciferase pr...

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Detalles Bibliográficos
Autores principales: Tang, Wei, Li, Yueyue, Song, Qiaoyun, Wang, Ziqin, Li, Manmei, Zhang, Qiwei, Wang, Ying, Ye, Wencai, Li, Yaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475503/
https://www.ncbi.nlm.nih.gov/pubmed/34379500
http://dx.doi.org/10.1128/JVI.01205-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475503/
https://www.ncbi.nlm.nih.gov/pubmed/34379500
http://dx.doi.org/10.1128/JVI.01205-21

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