The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia

TRAF1 is a pro-survival adaptor molecule in TNFR superfamily (TNFRSF) signaling. TRAF1 is overexpressed in many B cell cancers including refractory chronic lymphocytic leukemia (CLL). Little has been done to assess the role of TRAF1 in human cancer. Here we show that the protein kinase C related kin...

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Detalles Bibliográficos
Autores principales: Edilova, Maria I., Law, Jaclyn C., Zangiabadi, Safoura, Ting, Kenneth, Mbanwi, Achire N., Arruda, Andrea, Uehling, David, Isaac, Methvin, Prakesch, Michael, Al-awar, Rima, Minden, Mark D., Abdul-Sater, Ali A., Watts, Tania H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475556/
https://www.ncbi.nlm.nih.gov/pubmed/34589290
http://dx.doi.org/10.1080/2162402X.2021.1943234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475556/
https://www.ncbi.nlm.nih.gov/pubmed/34589290
http://dx.doi.org/10.1080/2162402X.2021.1943234

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