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The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia
TRAF1 is a pro-survival adaptor molecule in TNFR superfamily (TNFRSF) signaling. TRAF1 is overexpressed in many B cell cancers including refractory chronic lymphocytic leukemia (CLL). Little has been done to assess the role of TRAF1 in human cancer. Here we show that the protein kinase C related kin...
Autores principales: | Edilova, Maria I., Law, Jaclyn C., Zangiabadi, Safoura, Ting, Kenneth, Mbanwi, Achire N., Arruda, Andrea, Uehling, David, Isaac, Methvin, Prakesch, Michael, Al-awar, Rima, Minden, Mark D., Abdul-Sater, Ali A., Watts, Tania H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475556/ https://www.ncbi.nlm.nih.gov/pubmed/34589290 http://dx.doi.org/10.1080/2162402X.2021.1943234 |
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