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Monocyte-derived S1P in the lymph node regulates immune responses

The lipid chemoattractant sphingosine 1-phosphate (S1P) guides cells from the low-S1P environment of tissues into the high-S1P environment of circulatory fluids(1). Notably, S1P directs T cell exit from lymph nodes (LN), where T cells are initially activated, into lymph, from which T cells reach blo...

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Detalles Bibliográficos
Autores principales: Baeyens, Audrey A.L., Bracero, Sabrina, Chaluvadi, Venkata S., Khodadadi-Jamayran, Alireza, Cammer, Michael, Schwab, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475585/
https://www.ncbi.nlm.nih.gov/pubmed/33658712
http://dx.doi.org/10.1038/s41586-021-03227-6