The Effect of Population Structure on Murine Genome-Wide Association Studies

The ability to use genome-wide association studies (GWAS) for genetic discovery depends upon our ability to distinguish true causative from false positive association signals. Population structure (PS) has been shown to cause false positive signals in GWAS. PS correction is routinely used for analys...

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Detalles Bibliográficos
Autores principales: Wang, Meiyue, Fang, Zhuoqing, Yoo, Boyoung, Bejerano, Gill, Peltz, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475632/
https://www.ncbi.nlm.nih.gov/pubmed/34589118
http://dx.doi.org/10.3389/fgene.2021.745361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475632/
https://www.ncbi.nlm.nih.gov/pubmed/34589118
http://dx.doi.org/10.3389/fgene.2021.745361

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