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The Effect of Population Structure on Murine Genome-Wide Association Studies
The ability to use genome-wide association studies (GWAS) for genetic discovery depends upon our ability to distinguish true causative from false positive association signals. Population structure (PS) has been shown to cause false positive signals in GWAS. PS correction is routinely used for analys...
Autores principales: | Wang, Meiyue, Fang, Zhuoqing, Yoo, Boyoung, Bejerano, Gill, Peltz, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475632/ https://www.ncbi.nlm.nih.gov/pubmed/34589118 http://dx.doi.org/10.3389/fgene.2021.745361 |
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